Flinders Street Station is located on the corner of Flinders and Swanston Streets. It serves the entire metropolitan rail network as well as some country services to eastern Victoria and is the busiest station on Melbourne's metropolitan network and the busiest railway station in Australia.

Backing onto the Yarra River in the heart of the city, the complex includes platforms and structures that stretch over more than two whole city blocks, from east of Swanston Street nearly to Market Street.

The station's current main building was completed in 1909 and is a cultural icon of Melbourne. The distinctive and eclectic Edwardian building, with its prominent dome, arched entrance, tower and clocks is one of the city's most recognisable landmarks, and its grand, somewhat exotic character led to the popular myth that the design was actually intended for Mumbai's Victoria Terminus and vice versa, but was swapped in the post.

The Melbourne saying "I'll meet you under the clocks" refers to the row of indicator clocks above the main entrance, which show the next departure for each line; the alternative, "I'll meet you on the steps", refers to the wide staircase beneath the clocks.

It has been listed on the Victorian Heritage Register since 1982.